Pradeep Pradhan, Kanwar Sen and Priti Lal
Abstract:
Objective: To evaluate the effectiveness of Intratympanic dexamethasone in controlling vertigo and sensor neural hearing loss in intractable Meniere’s disease.
Methods: 30 patients with intractable Meniere’s disease were treated with intratympanic dexamethasone injections. Post treatment pure tone audiograms and dizziness scores were compared with the pretreatment audiogram and dizziness scores respectively.
Results: Improvement in mean vertigo score was noticed from 91.58 (range 80 -100) (pretreatment) to 49.295 (p=0.351) at 6 months and to 60.4 (p= 0.974) at the end of 2 years after intratympanic injection. 9 (40.90%) and 5 (25%) patients were found to be free of vertigo at the end of 06 months and 2 years respectively. None of the patients showed any significant improvement in hearing (>10dB) at the end of 2 years of follow-ups. Only one patient was found with a small central perforation at the end of 1 month of treatment.
Conclusion: Intratympanic steroid is a safe and an effective method of treating intractable Meniere’s disease. Although improvement in vertigo was more pronounced in the short term, 25% of the patients were detected free of vertigo at the end of 2 years. No significant improvement in hearing was noticed after 2 years of treatment.]
Objective: To evaluate the effectiveness of Intratympanic dexamethasone in controlling vertigo and sensor neural hearing loss in intractable Meniere’s disease.
Methods: 30 patients with intractable Meniere’s disease were treated with intratympanic dexamethasone injections. Post treatment pure tone audiograms and dizziness scores were compared with the pretreatment audiogram and dizziness scores respectively.
Results: Improvement in mean vertigo score was noticed from 91.58 (range 80 -100) (pretreatment) to 49.295 (p=0.351) at 6 months and to 60.4 (p= 0.974) at the end of 2 years after intratympanic injection. 9 (40.90%) and 5 (25%) patients were found to be free of vertigo at the end of 06 months and 2 years respectively. None of the patients showed any significant improvement in hearing (>10dB) at the end of 2 years of follow-ups. Only one patient was found with a small central perforation at the end of 1 month of treatment.
Conclusion: Intratympanic steroid is a safe and an effective method of treating intractable Meniere’s disease. Although improvement in vertigo was more pronounced in the short term, 25% of the patients were detected free of vertigo at the end of 2 years. No significant improvement in hearing was noticed after 2 years of treatment.]
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