Cristofaro Maria Giulia, Allegra Eugenia*, Trapasso Serena and Conforti Francesco
Abstract:
Background: The granular cell tumor (GCT), or Abrikossoff’s tumor, is a rare benign neoplasm of soft tissue a characterized by clusters of cells with abundant presence of cytoplasmic granules. It can affect any area of the body; in the head and neck, it has a predominance ranging from 45% to 65%; in 70% of these cases, it has intra-oral localization (tongue, oral mucosa, hard palate).
Case presentation: We describe a case of GCT of the tongue in a 47-year-old man presenting like a papillomatous lesion.
Discussion: Histopathological features, differential diagnosis, and therapeutic implications of GCT of the oral cavity are discussed, together with a review of the recent literature.
Conclusion: Immunochemistry besides helping to establish the correct diagnosis has allowed one to improve the knowledge of the controverter origin of this tumor, especially when clinical diagnosis is uncertain.
Background: The granular cell tumor (GCT), or Abrikossoff’s tumor, is a rare benign neoplasm of soft tissue a characterized by clusters of cells with abundant presence of cytoplasmic granules. It can affect any area of the body; in the head and neck, it has a predominance ranging from 45% to 65%; in 70% of these cases, it has intra-oral localization (tongue, oral mucosa, hard palate).
Case presentation: We describe a case of GCT of the tongue in a 47-year-old man presenting like a papillomatous lesion.
Discussion: Histopathological features, differential diagnosis, and therapeutic implications of GCT of the oral cavity are discussed, together with a review of the recent literature.
Conclusion: Immunochemistry besides helping to establish the correct diagnosis has allowed one to improve the knowledge of the controverter origin of this tumor, especially when clinical diagnosis is uncertain.
No comments:
Post a Comment